2024 World Conference on Lung Cancer (WCLC) - ePosters-EP.07D.05 Molecular Testing Care Gap Analysis of EGFR Mutation for Early-Stage NSCLC Patients in Community Practices

EP.07D.05 Molecular Testing Care Gap Analysis of EGFR Mutation for Early-Stage NSCLC Patients in Community Practices

Pdf Summary

The document outlines a study conducted to analyze the care gap in the administration of molecular testing, particularly EGFR mutation testing, for patients with early-stage non-small cell lung cancer (eNSCLC) within community healthcare practices. The analysis was conducted by a team associated with Tempus AI and partnered academic institutions. <br /><br />A total of 913 patients, aged 18-89, were included in this study, with data abstracted from over 120 elements within their clinical documents, including progress notes and pathology reports. These data were curated and verified through cross-checks with machine learning (ML) and artificial intelligence (AI) predictions, ensuring high data quality.<br /><br />The study reveals a significant gap in EGFR molecular testing for these patients, with notable adherence disparities when compared to late-stage NSCLC. Specifically, 33% of eligible early-stage non-squamous NSCLC patients do not receive EGFR testing, whereas this figure is only 11% for late-stage NSCLC patients, where molecular testing is a more established aspect of care. <br /><br />The study suggests that implementing healthcare interventions, such as automated care pathway tools, could bridge these gaps, aligning practice more closely with current National Comprehensive Cancer Network (NCCN) guidelines and improving patient outcomes.<br /><br />The results, derived from a de-identified real-world multimodal database, show consistent trends across four geographically diverse US sites, highlighting the universal nature of this care gap. The document advocates for enhanced use of both structured and unstructured electronic medical record data to gain comprehensive insights into patient journeys and identify clinically relevant care gaps.

Asset Subtitle

Jessica Dow

Meta Tag

Speaker Jessica Dow

Topic Early-Stage Non-small Cell Lung Cancer

Keywords

molecular testing

EGFR mutation

early-stage non-small cell lung cancer

eNSCLC

community healthcare

Tempus AI

machine learning

care gap

NCCN guidelines

electronic medical records