2024 World Conference on Lung Cancer (WCLC) - ePosters-EP.08E.06 The Peripheral Bronchial Occlusion or Stenosis after Dumon Y-stenting is Prognostic Factor in Patients with Advanced Lung Cancer

EP.08E.06 The Peripheral Bronchial Occlusion or Stenosis after Dumon Y-stenting is Prognostic Factor in Patients with Advanced Lung Cancer

Back to course

Pdf Summary

A study led by Tomohiko Higashiyama and his team from the Department of Thoracic Surgery at Osaka City General Hospital evaluated the prognostic factors following Dumon Y-stenting in patients with advanced lung cancer. This research focused particularly on peripheral bronchial patency—how open the peripheral airways remain after the stenting procedure.<br /><br />Y-stenting is a specific intervention used to relieve tracheobronchial stenosis, a common issue in advanced lung cancer where the airways become narrowed or blocked. This study involved a retrospective review of 116 patients who had Dumon Y-stents placed due to primary advanced lung cancer, drawn from a larger pool of 382 patients with airway stents indicated for central airway obstructions over the decade from 2012 to 2022.<br /><br />The findings highlighted that insufficient peripheral bronchial patency, such as occlusion or stenosis persisting after Y-stenting, serves as a significant independent prognostic factor. This condition adversely affects subsequent therapies in managing advanced lung cancer. Despite attempts to improve outcomes through customized or additional stenting, ensuring complete peripheral bronchial patency remains a challenge. Therefore, identifying effective airway interventions to maintain or restore patency is crucial.<br /><br />The study underscores the need for further research to determine the best interventions available that can support peripheral bronchial patency, considering this strongly affects patient prognosis and therapeutic success. The researchers drew on previous studies highlighting bronchoscopic and silicone Y-stent interventions to inform their investigation and reiterate the significance of maintaining patent airways for improving treatment outcomes and survival of patients with lung or esophageal cancers.<br /><br />Conclusively, the study calls for continued efforts and research to optimize stenting strategies and refine post-stenting therapies, as well as develop predictive models that can identify patients at greater risk of post-stent insufficient patency.

Asset Subtitle

Tomohiko Higashiyama

Meta Tag

Speaker Tomohiko Higashiyama

Topic Local-Regional Non-small Cell Lung Cancer

Keywords

Tomohiko Higashiyama

Dumon Y-stenting

advanced lung cancer

peripheral bronchial patency

tracheobronchial stenosis

prognostic factors

airway interventions

retrospective review

silicone Y-stent

post-stenting therapies