2024 World Conference on Lung Cancer (WCLC) - ePosters-EP.09A.04 Enhancing Radiotherapy Efficacy for Brain Metastases in Non-Small Cell Lung Cancer Through the Integration of G-CSF and Immunotherapy

EP.09A.04 Enhancing Radiotherapy Efficacy for Brain Metastases in Non-Small Cell Lung Cancer Through the Integration of G-CSF and Immunotherapy

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The study presented by Gong Xiaomei from the Department of Radiation Oncology at Shanghai Pulmonary Hospital analyzed the effectiveness of combining Granulocyte-Colony Stimulating Factor (G-CSF) with whole-brain radiotherapy (WBRT) and immunotherapy for patients with brain metastases from non-small cell lung cancer (NSCLC). Results indicate that patients receiving this combined treatment experienced significant improvements in overall survival (OS) and symptom relief from brain metastases compared to those who did not receive G-CSF. The findings suggest that integrating G-CSF with radiotherapy and immunotherapy as a first-line treatment can significantly enhance therapeutic efficacy for NSCLC patients with brain metastases, leading to better clinical outcomes by extending survival and alleviating related symptoms.

Asset Subtitle

Xiaomei Gong

Meta Tag

Speaker Xiaomei Gong

Topic Metastatic Non-small Cell Lung Cancer – Local Therapies

Keywords

Granulocyte-Colony Stimulating Factor

G-CSF

whole-brain radiotherapy

WBRT

immunotherapy

brain metastases

non-small cell lung cancer

NSCLC

overall survival

symptom relief