2024 World Conference on Lung Cancer (WCLC) - ePosters-EP.09A.07 Prognostic Factors for Advanced Invasive Mucinous Adenocarcinoma of the Lung with Emphasis on the Treatment Modalities

EP.09A.07 Prognostic Factors for Advanced Invasive Mucinous Adenocarcinoma of the Lung with Emphasis on the Treatment Modalities

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The study by Soo Han Kim and colleagues from the Pusan National University Hospital investigates the prognosis and treatment modalities for advanced invasive mucinous adenocarcinoma (IMA) of the lung, a rare subtype of lung adenocarcinoma. Despite its rarity, understanding the prognosis for advanced IMA stages has been limited. This research aims to evaluate prognostic factors and assess treatment approaches in such cases.<br /><br />The study is a retrospective analysis conducted at a single center, encompassing 33 patients diagnosed at advanced stages or those who progressed after initially curative treatment between 2011 and 2021. Of these, 13 patients were at an initial advanced stage while 20 patients experienced progression post-curative intervention. The primary outcome measured was overall survival (OS), and the secondary outcome was progression-free survival (PFS), both calculated from the diagnosis date of advanced IMA.<br /><br />The study underscores that local ablative therapy could potentially offer favorable survival outcomes for patients with advanced IMA; however, it might not be as effective when addressing cancer progression. This suggests the possibility of a differential benefit based on treatment timing and status of disease advancement.<br /><br />In summary, the findings present a significant insight into how therapeutic strategies might influence survival outcomes in advanced IMA cases. Future research and clinical strategies could focus on integrating local ablative treatments more effectively in patient management protocols to potentially extend survival while acknowledging the complexity of managing cancer progression.

Asset Subtitle

Soo Han Kim

Meta Tag

Speaker Soo Han Kim

Topic Metastatic Non-small Cell Lung Cancer – Local Therapies

Keywords

advanced invasive mucinous adenocarcinoma

lung adenocarcinoma

prognosis

treatment modalities

overall survival

progression-free survival

local ablative therapy

retrospective analysis

Pusan National University Hospital

therapeutic strategies