2024 World Conference on Lung Cancer (WCLC) - ePosters-EP.14C.01 Coexisting Pulmonary Tuberculosis and Primary Lung Cancer: Prevalence of Diagnostic, Treatment and Outcome

EP.14C.01 Coexisting Pulmonary Tuberculosis and Primary Lung Cancer: Prevalence of Diagnostic, Treatment and Outcome

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The document focuses on a study examining the coexistence of pulmonary tuberculosis (TB) and lung cancer (LC) in Vietnam. It highlights the diagnostic challenges and treatment implications due to this coexistence. Key demographic and clinical features are presented for 52 patients, showing a median age of 59.2 years, with most being male (71.2%) and current smokers (81.8%). Lung cancer types include squamous cell carcinoma (50%), adenocarcinoma (21.2%), and small cell lung cancer (23.1%), with stages III and IV being most common (38.5% each).<br /><br />The study underscores that Vietnam has a high burden of TB, ranking 11th globally. This complicates the diagnosis and treatment of lung cancer, as TB can mask cancer symptoms, delaying diagnosis and affecting patient outcomes. Delay in diagnosis averages 3.6 months, with common symptoms being chest pain (55.8%) and prolonged dry cough (61.3%). Diagnostic methods include lung tissue culture and H&E staining (73.1%) and biopsy (23.1%). Imaging often shows cavities (78.8%) and separate nodules (86.5%).<br /><br />The results emphasize TB's role as a significant concern, particularly in male patients with heavy smoking habits in TB-endemic regions. The presence of TB can obscure underlying lung cancer, leading to delayed treatment and poorer outcomes. The study concludes by stressing the need for careful diagnosis and management of these patients to improve treatment efficacy.<br /><br />Overall, the study sheds light on the clinical and diagnostic challenges faced when dealing with coexisting TB and LC, offering insights into patient demographics, presentation, and the impact on survival.

Asset Subtitle

Anh Dinh

Meta Tag

Speaker Anh Dinh

Topic Mesothelioma, Thymoma, and Other Thoracic Tumors

Keywords

pulmonary tuberculosis

lung cancer

Vietnam

diagnostic challenges

treatment implications

demographics

smoking

diagnosis delay

imaging findings

TB-endemic regions