2024 World Conference on Lung Cancer (WCLC) - ePosters-EP.14C.05 The Management of Solitary Fibrous Tumors of Chest in a Center

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The document provides an overview and analysis of Solitary Fibrous Tumors (SFTs) within the Department of Thoracic Surgery at the General Hospital of Athens from 2019 to 2023. SFTs are rare tumors originating from mesenchymal cells, typically found in the pleura. They equally affect males and females, commonly appearing in the fifth to seventh decades of life. Computed Tomography (CT) is the diagnostic gold standard, showing SFT as well-circumscribed masses with potential enhancement post-contrast administration. <br /><br />Histologically, SFTs consist of spindle-shaped cells within a collagenous stroma and are distinguished by specific biomarkers like CD34, Bcl-2, and STAT6. The complete surgical resection is the preferred treatment, given the high survival rate and good prognosis, as these tumors predominantly exhibit benign behavior with low recurrence and metastatic potential.<br /><br />In a study sample of ten patients, equal numbers of men and women were treated, with a mean age of 65.4 years. Tumors were either found in the right or left hemithorax, with a mean size of 6.57 cm. Most patients underwent video-assisted thoracoscopy, while a smaller group had open surgery. Based on the Demicco score, which assesses metastatic risk, the majority had a low risk, and none showed metastasis during follow-up.<br /><br />The document asserts that SFTs are mainly non-recurrent and benign, with a significant survival rate, especially when tumors are completely resected. It emphasizes the importance of surgical intervention over chemotherapy or radiation, which is generally reserved for advanced cases. Monitoring involves periodic CT scans post-treatment to check for recurrences. Overall, the department's findings align with larger studies regarding the management and outcomes of SFTs, confirming their low metastatic potential and excellent prognosis post-surgery.

Asset Subtitle

Ioannis Vathiotis

Meta Tag

Speaker Ioannis Vathiotis

Topic Mesothelioma, Thymoma, and Other Thoracic Tumors

Keywords

Solitary Fibrous Tumors

Thoracic Surgery

General Hospital of Athens

mesenchymal cells

Computed Tomography

CD34 biomarker

surgical resection

video-assisted thoracoscopy

Demicco score

low metastatic potential