PP01.07: Identification of Synthetic Lethal Vulnerabilities Between TRIM28 and NOTCH2 in Small Cell Lung Cancer Through CRISPR/Cas9 Screening
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Pdf Summary
Asset Subtitle
Deli Hong
Keywords
Small Cell Lung Cancer
SCLC
NOTCH mutations
CRISPR/Cas9
synthetic lethality
TRIM28
endogenous retroviruses
STING1/MAVS-TBK1 pathway
tumor growth inhibition
therapeutic target
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