Best Practices and Research Advances in Thoracic Oncology: A Regional Series MENA Course 1: Liquid Biopsy in Lung Cancer-A Practical Case to Open Debate

Video Transcription

Video Summary

Dr. Tahir Abu Hijleh, a thoracic oncologist, presented a clinical case highlighting the use of circulating tumor DNA or liquid biopsy in non-small cell lung cancer. A late 50s heavy smoker was diagnosed with extensive-stage small cell lung cancer after presenting with chest pain and a cough. Subsequent treatments were ineffective, confirming a diagnosis shift to SMARC A4 deficient undifferentiated tumor. Liquid biopsy provided a fast alternative to tissue-based testing, confirming this rare diagnosis while excluding actionable mutations. Despite treatments, the aggressive cancer led to the patient's passing. Future presentations will explore the role of liquid biopsy in the MENA region.

Asset Subtitle

Taher Abu Hejleh, MBBS, MS

Meta Tag

Concept Circulating Tumor DNA

Concept Liquid Biopsy

Concept Tissue-Based Next-Generation Sequencing

Concept Non-Small Cell Lung Cancer

Concept Actionable Mutation

Keywords

liquid biopsy

non-small cell lung cancer

circulating tumor DNA

SMARC A4 deficient tumor

thoracic oncology

Circulating Tumor DNA

Liquid Biopsy

Tissue-Based Next-Generation Sequencing

Non-Small Cell Lung Cancer

Actionable Mutation