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Best Practices and Research Advances in Thoracic O ...
Molecular Profiling in the Region: Opportunities & ...
Molecular Profiling in the Region: Opportunities & Challenges
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Video Summary
Rina Hui, from the University of Hong Kong, emphasizes the significance of molecular profiling in tackling high cancer rates in Asia, where over 60% of lung cancer cases are diagnosed. She highlights how identifying genetic mutations, such as EGFR and ALK, has revolutionized non-small cell lung cancer treatments. Various targeted therapies, including Osimertinib and Alatinib, have significantly extended survival rates, with 60% of metastatic ALK-positive patients now living beyond five years. However, Hui points out challenges like cost and access to molecular testing in low-income Asian countries. Disparities exist in biomarker testing, with lower-income regions showing lower testing rates and starting treatments before biomarker results. Molecular tumor boards, integrating expertise from various fields, are proposed as essential for optimizing treatments and overcoming healthcare disparities. Emphasizing Asia's unique genetic profiles, Hui calls for improved access to molecular testing and targeted therapies to improve patient outcomes.
Keywords
molecular profiling
lung cancer
targeted therapies
biomarker testing
healthcare disparities
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