Current Approaches and Future Directions in Radiotherapy for Small Cell Lung Cancer (SCLC)-Current Approaches and Future Directions in Radiotherapy for Small Cell Lung Cancer (SCLC)

Current Approaches and Future Directions in Radiotherapy for Small Cell Lung Cancer (SCLC)

Video Transcription

Video Summary

The speakers discussed the current treatment strategies for small cell lung cancer, particularly in the limited stage and extensive stage settings. They emphasized the importance of incorporating radiotherapy and systemic therapy in the management of small cell lung cancer. In the limited stage, the standard of care is platinum-etoposide chemotherapy with thoracic radiation, followed by prophylactic cranial irradiation (PCI) . The use of hippocampal avoidance during radiation therapy was also discussed as a way to decrease neurocognitive toxic effects. In the extensive stage, the role of PCI is still being debated, and ongoing trials are evaluating its efficacy in the era of immunotherapy. The use of stereotactic radiosurgery was also mentioned as a treatment option for patients with brain metastases. The speakers highlighted the need for further research, such as the ongoing clinical trials, to improve outcomes and identify biomarkers for treatment selection. Overall, the webinar provided insight into the evolving treatment landscape for small cell lung cancer.

Keywords

small cell lung cancer

treatment strategies

limited stage

extensive stage

radiotherapy

systemic therapy

platinum-etoposide chemotherapy

thoracic radiation

prophylactic cranial irradiation