WCLC 2025 - Posters & ePosters-P2.15 .07 Effect of Message Framing in a Digital Lung Cancer Screening Decision Navigation Intervention: A Three-Arm Randomized Controlled Trial

P2.15 .07 Effect of Message Framing in a Digital Lung Cancer Screening Decision Navigation Intervention: A Three-Arm Randomized Controlled Trial

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This randomized controlled trial assessed the effects of message framing within a digital lung cancer screening (LCS) decision navigation intervention in a Chinese high-risk population. Researchers developed China’s first LCS patient decision aid (PDA), the LCS Loss-Gain Balance (LCS-LG-B), which incorporates gain-framed messaging (emphasizing screening benefits) and loss-framed messaging (highlighting consequences of not screening). The study enrolled 189 participants randomized equally into three groups: loss-framed, gain-framed, and control. Outcomes measured included low-dose CT (LDCT) uptake, decision conflict, self-efficacy, decision preparation, lung cancer screening knowledge, and health beliefs, assessed from baseline up to six months post-intervention.<br /><br />Results showed that both message-framed intervention groups significantly improved decision quality indicators—reducing decision conflict and enhancing self-efficacy, decision preparation, and perceived risk—compared to controls. The gain-framed group demonstrated higher decision preparation across multiple follow-ups, whereas the loss-framed group exhibited increased perceived barriers at one month but higher perceived benefits and self-efficacy immediately post-intervention. Crucially, LDCT uptake was significantly greater in the intervention groups: 53.7% in loss-framed, 42.6% in gain-framed, versus 16.1% in controls.<br /><br />This pioneering study demonstrates that framing messages around gains or losses effectively enhances informed decision-making and promotes lung cancer screening uptake among high-risk individuals in China. By integrating shared decision-making, patient navigation, and cognitive framing in a digital platform, the intervention supports early detection efforts. The authors recommend future research to investigate long-term impacts and scalability across diverse populations. Funded by the National Natural Science Foundation of China, this work contributes valuable evidence on utilizing message framing within decision aids to improve lung cancer screening participation and outcomes.

Asset Subtitle

Feifei Huang

Meta Tag

Speaker Feifei Huang

Topic Multidisciplinary Care: Nursing, Allied Health and Palliative Care

Keywords

lung cancer screening

message framing

randomized controlled trial

digital intervention

decision aid

gain-framed messaging

loss-framed messaging

low-dose CT uptake

self-efficacy

Chinese high-risk population