Virtual Tumor Board: EGFR-mutant NSCLC

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VIKTOR

Podcast | English | 2026 | 47 Min

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In this episode of Lung Cancer Considered, host Dr. Stephen Liu is joined by Dr. Sara Pilotto and Dr. Jonathan Riess for a virtual tumor board discussion on the management of metastatic EGFR exon 19 NSCLC . Using a complex case featuring discordant biomarker results and brain metastases, the panel explores first-line treatment strategies including osimertinib monotherapy, FLAURA2 (osimertinib plus chemotherapy), and MARIPOSA (amivantamab plus lazertinib), as well as sequencing at progression, re-biopsy, CNS considerations, and the evolving role of local consolidation and clinical trials.

Podcast Hosts:

Stephen Liu, MD, Chief, Hematology & Oncology, Head, Developmental Therapeutics, MedStar Georgetown University Hospital, Lombardi Comprehensive Cancer Center, Washington, D.C., USA

Podcast Guests:

Sara Pilotto, MD, PhD, Associate Professor, Medical Oncology, University of Verona, Italy
Jonathan Riess, MD, Director, Thoracic Oncology, UC Davis Cancer Center, University of California Davis, Sacramento, CA, USA