As part of IASLC's ongoing series of podcasts in world languages, Dr. Ece Cali Daylan moderates a discussion in Turkish with Dr. Özden Altundağ and Dr. Saadettin Kiliçkap. This episode reviews the first-line treatment approaches for metastatic NSCLC with common activating EGFR mutations through a case-based discussion. It highlights key data from the FLAURA, FLAURA-2, and MARIPOSA trials, and discusses practical considerations in managing brain metastases and drug toxicities.