This case study delves into the comprehensive understanding of pleural mesothelioma, focusing on contemporary diagnostic methodologies and the evolving landscape of immunotherapy in its management. The microcourse highlights the paradigm shift in treatment strategies with the advent of immunotherapeutic interventions, examining the mechanisms, efficacy, and limitations of immunotherapy in combating this complex disease.

Thoracic oncologists, pathologists and researchers.

Upon completion of this activity, the participants should be able to: 

• Recognize that tissue biopsy is needed in order to determine histologic subtype of pleural mesothelioma.
• Choose systemic therapy based on histologic subtype of pleural mesothelioma.
• Implement and escalate immunosuppression to manage immune-related side effects of immunotherapy.
• Recognize when immunotherapy should be permanently discontinued in favor of surveillance

• Melina Marmarelis, MD, MSCE, University of Pennsylvania, Philadelphia, PA, USA

The information presented is that of the contributing faculty and does not necessarily represent the views of the International Association for the Study of Lung Cancer and/or any named commercial entity providing financial support. Specific therapies discussed may not be approved and/or specified for use as indicated by the faculty presenters. Therefore, before prescribing any medication, please review the complete prescribing information, including indications, contraindications, warnings, precautions, and adverse effects.

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

If you need any assistance with this activity, please email: education@iaslc.org.