2023 World Conference on Lung Cancer (Posters)-EP01.01. Poor Sleep Quality in Lung Cancer Patients

Pdf Summary

A study presented at the WCLC 2023 conference explored the relationship between poor sleep quality and lung cancer in patients. Sleep disturbances have been observed in lung cancer patients and can greatly impact their daily functioning and quality of life. Factors contributing to sleep disturbances in these patients include gender, age, prior sleep history, type and stage of lung cancer, pain, treatment side effects, and poor sleep hygiene. Obstructive sleep apnea (OSA) is a common sleep problem in lung cancer patients, characterized by episodes of breathing cessation during sleep. The apnea hypopnea index (AHI) is used to diagnose OSA, and patients often experience symptoms such as fatigue, sleepiness, and morning headaches. Screening questionnaires can help identify those at high risk of OSA for further evaluation. The study evaluated sleep quality and daytime functioning in 151 newly diagnosed lung cancer outpatients using three sleep questionnaires. It found that 80.13% of patients were at low risk of OSA, while 19.87% were at high risk. OSA is associated with intermittent hypoxia, which can cause damage at the tissue and systemic levels. Hypoxia-inducible factor (HIF-1), a transcription factor activated during hypoxia, is linked to angiogenesis, invasion, metastasis, and cancer stem cell maintenance. The study suggests a potential relationship between OSA and lung cancer, with evidence indicating that OSA may be a risk factor for cancer development. Additionally, poor sleep quality can significantly impair the quality of life in the lung cancer population. Further research is warranted to better understand this association and develop interventions to improve sleep quality and outcomes in lung cancer patients.

Asset Subtitle

Andika Putra

Meta Tag

Speaker Andika Putra

Topic Risk Factors, Risk Reduction & Tobacco Control

Keywords

poor sleep quality

lung cancer patients

sleep disturbances

obstructive sleep apnea

apnea hypopnea index

fatigue

screening questionnaires

high risk of OSA

hypoxia-inducible factor

improve sleep quality