2023 World Conference on Lung Cancer (Posters)-EP07.03. Non-Small Cell Lung Cancer in Obese Patients: Comparison of Open, Robotic and Videothoracoscopic Surgery. A Multicenter Retrospective Series

EP07.03. Non-Small Cell Lung Cancer in Obese Patients: Comparison of Open, Robotic and Videothoracoscopic Surgery. A Multicenter Retrospective Series - PDF(Slides)

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A multicenter retrospective study compared the outcomes of different surgical approaches for obese patients with Non-Small Cell Lung Cancer (NSCLC). The study aimed to compare the Robotic-assisted (RATS) approach, Video-assisted (VATS) thoracic surgery, and the open approach (OA) in terms of post-operative complications, surgical-related risks, and short-term oncologic outcomes.<br /><br />The study analyzed data from 279 patients with a Body Mass Index (BMI) of 30 kg/m2 or higher who underwent anatomical lung resection for early-stage NSCLC between 2013 and 2022. The patients were divided into three groups: RATS, VATS, and OA. The primary outcomes assessed were post-operative complication rate, length of hospital stay, length of chest drain, in-hospital, 30-day, and 90-day mortality, and estimated intraoperative blood loss. The secondary outcomes included conversion rate, harvested lymph node stations, nodal upstaging rate, and operating time.<br /><br />The study found that both RATS and VATS approaches were associated with significantly lower post-operative complication rates, shorter lengths of hospital stay and chest drain compared to the OA. There were no significant differences in terms of hospital, 30-day, and 90-day mortality rates among the three approaches. The RATS approach had a significantly lower estimated intraoperative blood loss compared to both VATS and OA. Additionally, the RATS approach resulted in a higher median number of overall, N1, and N2 lymph node stations harvested compared to VATS and OA. The operating time was also significantly shorter in the RATS group.<br /><br />In conclusion, for obese patients undergoing anatomical lung resection for early-stage NSCLC, both RATS and VATS approaches offer advantages over the open approach in terms of lower post-operative complications and shorter hospital stays. The RATS approach also showed advantages in terms of estimated intraoperative blood loss, operating time, and the number of lymph node stations harvested. However, there were no significant differences in mortality rates between the approaches.

Asset Subtitle

Andrea Bille

Meta Tag

Speaker Andrea Bille

Topic Early-Stage NSCLC: Limited Resections & Minimally Invasive Approaches

Keywords

multicenter study

obese patients

NSCLC

surgical approaches

post-operative complications

hospital stay

intraoperative blood loss

lymph node stations

operating time

mortality rates