2023 World Conference on Lung Cancer (Posters)-EP07.04. Analysis of Radiologic-Pathologic Correlation for Subsolid Lung Adenocarcinoma Using the Whole-Mount Section Technique: A Prospective Study

EP07.04. Analysis of Radiologic-Pathologic Correlation for Subsolid Lung Adenocarcinoma Using the Whole-Mount Section Technique: A Prospective Study - PDF(Abstract)

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This study aimed to analyze the radiologic-pathologic correlation for subsolid lung adenocarcinoma using the whole-mount section technique. The researchers conducted a prospective clinical study with 102 patients who underwent segmentectomy or lobectomy for subsolid lung adenocarcinoma. Pathologic whole-mount sections were made and digitized, and similar radiologic and pathologic cross sections of the tumors were identified and matched.<br /><br />The results showed that the radiologic tumor size was larger than the pathologic tumor size, while the radiologic solid component size was smaller than the pathologic invasive component size. For pure ground glass opacity (GGO) tumors, in addition to the lepidic subtype, there were invasive parts mainly consisting of acinar and papillary subtypes. No micropapillary or solid subtypes were found. <br /><br />For part-solid tumors, the GGO region had lepidic, acinar, papillary, and micropapillary subtypes. In the solid region, there were lepidic, acinar, papillary, micropapillary, and solid subtypes. <br /><br />These findings provide insight into the histologic features of subsolid lung adenocarcinoma and contribute to a better understanding of the radiologic-pathologic correlation. The study highlights the importance of considering both radiologic and pathologic features for accurate diagnosis and treatment planning for patients with subsolid lung adenocarcinoma.

Asset Subtitle

Chaoqiang Deng

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Speaker Chaoqiang Deng

Topic Early-Stage NSCLC: Progress in Pathology

Keywords

radiologic-pathologic correlation

subsolid lung adenocarcinoma

whole-mount section technique

prospective clinical study

segmentectomy

lobectomy

ground glass opacity (GGO)

lepidic subtype

acinar subtype

papillary subtype