2023 World Conference on Lung Cancer (Posters)-EP07.04. Pleural CEA and SUVmax as Predictors of Visceral Pleural Invasion in Clinical T1N0M0 Lung Adenocarcinoma

EP07.04. Pleural CEA and SUVmax as Predictors of Visceral Pleural Invasion in Clinical T1N0M0 Lung Adenocarcinoma - PDF(Abstract)

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In this study, the researchers aimed to determine if pleural carcinoembryonic antigen (pCEA) levels can predict visceral pleural invasion (VPI) in patients with early-stage lung adenocarcinoma. They retrospectively analyzed data from 432 patients diagnosed with clinical stage I adenocarcinoma who had undergone lung resection surgery. The researchers found that 65 patients (15.0%) had positive VPI. Using receiver operating characteristic (ROC) curve analysis, they determined that the upper limit for pCEA suggesting VPI was 1.86 ng/mL. Based on this value, they found that 33.3% of patients had pCEA levels above the upper limit. Logistic regression analysis confirmed that pCEA and maximum standardized uptake value (SUVmax) were significant predictors of VPI. The researchers concluded that pCEA can be a useful factor in predicting VPI in early-stage lung adenocarcinoma patients. They suggest that if significant positive pCEA is detected during surgery, it indicates the presence of VPI and can help guide the selection of the surgical plan. This study highlights the potential for utilizing pCEA levels as a predictor of VPI in lung adenocarcinoma patients, providing valuable information for surgical decision-making.

Asset Subtitle

GaYoung Yoo

Meta Tag

Speaker GaYoung Yoo

Topic Early-Stage NSCLC: Progress in Pathology

Keywords

pleural carcinoembryonic antigen

pCEA levels

visceral pleural invasion

early-stage lung adenocarcinoma

lung resection surgery

receiver operating characteristic curve analysis

upper limit

predictors of VPI

maximum standardized uptake value

surgical decision-making