2023 World Conference on Lung Cancer (Posters)-EP13.02. Minimally Invasive Surgery for Endobronchial Small Cell Lung Carcinoma following Neoadjuvant Chemotherapy

EP13.02. Minimally Invasive Surgery for Endobronchial Small Cell Lung Carcinoma following Neoadjuvant Chemotherapy - PDF(Slides)

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This article discusses two cases of endobronchial small cell lung cancer treated with minimally invasive surgery following neoadjuvant chemotherapy. The first patient was a 60-year-old male with an obstructing tumor in the right upper lobe. After biopsies confirmed small cell lung cancer, staging tests showed no lymph node invasion. The patient received two cycles of preoperative chemotherapy before undergoing a VATS right upper sleeve lobectomy and full mediastinal lymph node dissection. The final histology revealed a T1c tumor with no lymph node invasion. The second patient was a 65-year-old female with a pure endobronchial small cell tumor. Staging tests also showed no distant disease or mediastinal involvement. This patient received both preoperative and postoperative chemotherapy before undergoing a Biportal VATS technique. The tumor, located near the origin of the lower lobe bronchus, was removed by stapling the bronchus, and a mediastinal lymph node dissection was performed. Both patients recovered well and showed no signs of disease one year after diagnosis. The authors conclude that a multimodality approach and minimally invasive surgery, such as sleeve lobectomy with bronchial anastomosis, can offer advantages over pneumonectomy, reducing postoperative complications. They also note the rarity of limited stage small cell lung carcinomas with bronchial involvement and the potential benefits of an aggressive treatment approach in these cases.

Asset Subtitle

Konstantinos Konstantinidis

Meta Tag

Speaker Konstantinos Konstantinidis

Topic SCLC & Neuroendocrine Tumors: Case Report

Keywords

endobronchial small cell lung cancer

minimally invasive surgery

neoadjuvant chemotherapy

VATS

lobectomy

mediastinal lymph node dissection

T1c tumor

pure endobronchial small cell tumor

Biportal VATS technique

multimodality approach