2023 World Conference on Lung Cancer (Posters)-EP17.02. Concordance on Treatment Recommendations from Multidisciplinary Tumor Boards -Data from Driver-Mutated Lung Cancer in Focus

EP17.02. Concordance on Treatment Recommendations from Multidisciplinary Tumor Boards -Data from Driver-Mutated Lung Cancer in Focus - PDF(Abstract)

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This study investigates the concordance on treatment recommendations from multidisciplinary tumor boards (MTB) in patients with driver-mutated lung cancer. The aim is to determine the frequency of different degrees of concordance (full, partial, non-concordance), differences in concordance in driver-mutated patients, and the overall survival associated with different degrees of concordance.<br /><br />Data from 622 lung cancer patients discussed in tumor boards at a certified lung cancer center in Northern Germany were analyzed. Out of these patients, 12% (75/644) had a driver mutation. The overall concordance rate was found to be 85%, with 9% showing partial concordance and 6% showing non-concordance.<br /><br />When comparing driver-mutated patients to the overall cohort, it was found that patients with a driver mutation had a higher concordance rate of 91%. Patients with a complete concordance to the tumor board recommendation had an overall survival of 17 months, compared to 5 months for patients with partial concordance and 4 months for patients with discordant treatment.<br /><br />The study concludes that patients with concordant treatment have a significantly longer overall survival compared to those with discordant treatment. The concordance rate is higher in driver-mutated patients, and those with a driver mutation and concordant treatment have a longer overall survival compared to patients without a driver mutation.<br /><br />The authors suggest that assessing concordance to MTB recommendations could be a meaningful quality criterion for cancer centers in Germany. This research highlights the importance of multidisciplinary tumor boards in developing the best possible treatment plans for lung cancer patients.

Asset Subtitle

Julia Roeper

Meta Tag

Speaker Julia Roeper

Topic Global Health, Health Services & Health Economics: Health Care Utilization

Keywords

multidisciplinary tumor boards

treatment recommendations

driver-mutated lung cancer

concordance

overall survival

driver mutation

certified lung cancer center

discordant treatment

quality criterion

treatment plans