2023 World Conference on Lung Cancer (Posters)-P1.16. Transbronchial Cryobiopsy Using 1.1 mm-Diameter Cryoprobe for the Diagnosis of Early Stage Lung Cancer

P1.16. Transbronchial Cryobiopsy Using 1.1 mm-Diameter Cryoprobe for the Diagnosis of Early Stage Lung Cancer - PDF(Abstract)

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The study presented in this document focuses on the use of transbronchial cryobiopsy (TBCB) as a diagnostic technique for peripheral lung lesions (PLLs), specifically in the early stages of lung cancer. The researchers conducted a prospective observational pilot study involving 50 patients with PLLs. The TBCB procedure was performed using a 1.1-mm diameter cryoprobe along with radial endobronchial ultrasound, virtual bronchoscopic navigation, and fluoroscopy.<br /><br />The primary outcome of the study was the pathological diagnostic yield of TBCB, while the secondary outcome was adverse events related to the procedure. The results showed that TBCB had an overall diagnostic yield of 92%, with 45 out of 49 patients diagnosed correctly. The diagnostic yield rates for the first, second, and third TBCB procedures were 84%, 74%, and 62%, respectively. The cumulative diagnostic yield increased from 84% to 90% to 92% with each subsequent TBCB procedure.<br /><br />In terms of adverse events, mild bleeding occurred in 57% of patients, while moderate bleeding occurred in 27% of patients. However, there were no cases of pneumothorax or other life-threatening complications.<br /><br />Based on these findings, the researchers concluded that TBCB using a 1.1-mm diameter cryoprobe is an effective and safe method for diagnosing PLLs, including early-stage lung cancer. This technique has a high diagnostic yield and does not pose any significant risks to patients.<br /><br />The keywords associated with this study are peripheral lung lesion, early-stage lung cancer, and cryobiopsy. The research falls under the track of screening and early detection, and the abstract is categorized as a regular abstract.

Asset Subtitle

Jung Seop Eom

Meta Tag

Speaker Jung Seop Eom

Topic Screening & Early Detection: Nodule Management

Keywords

transbronchial cryobiopsy

TBCB

peripheral lung lesions

PLLs

early-stage lung cancer

diagnostic yield

adverse events

1.1-mm diameter cryoprobe

radial endobronchial ultrasound

screening and early detection