2023 World Conference on Lung Cancer (Posters)-P1.25. Surgical Outcomes in Patients with Resected Node-negative Lung Adenocarcinoma of 2 cm or Smaller

P1.25. Surgical Outcomes in Patients with Resected Node-negative Lung Adenocarcinoma of 2 cm or Smaller - PDF(Slides)

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This study investigated the prognostic factors for patients with surgically resected, node-negative lung adenocarcinoma that is 2 cm or smaller. A total of 599 patients were included in the study, and recurrence occurred in 6.3% of the patients during the follow-up period.<br /><br />The results from the study showed that age, tumor size, visceral pleural invasion, and the micropapillary/solid predominant pattern were significant prognostic factors for the probability of freedom from recurrence (FFR) in patients with node-negative lung adenocarcinoma that is 2 cm or smaller. However, the extent of pulmonary resection (wedge resection versus anatomical resection) did not have a significant impact on the probability of FFR.<br /><br />Multivariate analysis further confirmed that older age, larger tumor size, and the micropapillary/solid predominant pattern were associated with a significantly lower probability of FFR. Additionally, patients with lepidic-predominant adenocarcinoma had a high 5-year probability of FFR (97.5%).<br /><br />The study concluded that although patients with node-negative lung adenocarcinoma that is 2 cm or smaller generally have a good prognosis after surgical resection, certain factors such as older age, larger tumor size, and the micropapillary/solid predominant pattern are associated with a higher risk of recurrence. This information can be useful in identifying patients who may benefit from adjuvant therapy.

Asset Subtitle

Jung-Jyh Hung

Meta Tag

Speaker Jung-Jyh Hung

Topic Early-Stage NSCLC: Changing Paradigms & Outcomes

Keywords

prognostic factors

surgical resection

node-negative

lung adenocarcinoma

2 cm or smaller

recurrence

age

tumor size

micropapillary/solid pattern

adjuvant therapy