2023 World Conference on Lung Cancer (Posters)-P1.25. Trends and Disparities in Curative-Intent Treatment for Early-Stage Non-Small Cell Lung Cancer: A Population-Based Analysis of Surgery and SBRT

P1.25. Trends and Disparities in Curative-Intent Treatment for Early-Stage Non-Small Cell Lung Cancer: A Population-Based Analysis of Surgery and SBRT - PDF(Abstract)

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This study examines trends and disparities in curative-intent treatment for early-stage non-small cell lung cancer (NSCLC) using population-based data from the Florida cancer registry. The study focuses on the adoption of stereotactic body radiotherapy (SBRT) as an alternative treatment and its impact on racial/ethnic disparities. The data includes information on patient demographics, comorbidities, and treatment.<br /><br />The results show that among the 63,872 early-stage NSCLC patients analyzed, 72.2% received curative-intent treatment, which includes surgery and/or SBRT. The percentage of Hispanic and White patients receiving curative-intent treatment was higher than Black patients, with 73.7% for Hispanics, 73.0% for Whites, and only 60.8% for Blacks.<br /><br />The study also found that the use of SBRT increased annually by 8.1% from 2007 to 2017, while the use of curative-intent surgery declined during 2014-2017. After adjusting for sociodemographic and clinical factors, the odds of Black patients receiving curative-intent surgery were 29% lower than White patients, while Hispanic patients had 17% higher odds.<br /><br />Despite the availability of SBRT, racial disparities in receiving curative-intent treatment for early-stage NSCLC persist. Additionally, approximately 28% of patients across all races do not undergo curative-intent treatment, suggesting that the full potential of SBRT remains unachieved.<br /><br />The study suggests that further research is needed to understand the reasons behind these disparities, particularly focusing on treatment decision-making, patient-provider communication, and treatment compliance/refusal among Black patients with early-stage NSCLC. The findings highlight the need for interventions that address these disparities and ensure equitable access to curative-intent treatment for all patients.

Asset Subtitle

Estelamari Rodriguez

Meta Tag

Speaker Estelamari Rodriguez

Topic Early-Stage NSCLC: Changing Paradigms & Outcomes

Keywords

curative-intent treatment

early-stage non-small cell lung cancer

NSCLC

stereotactic body radiotherapy

SBRT

racial/ethnic disparities

patient demographics

comorbidities

treatment adoption

sociodemographic factors