2023 World Conference on Lung Cancer (Posters)-P1.27. Two- and Three-dimensional Radiomic Measurements for Clinical Stage IA Lung Adenocarcinoma: Less is More

P1.27. Two- and Three-dimensional Radiomic Measurements for Clinical Stage IA Lung Adenocarcinoma: Less is More - PDF(Abstract)

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This presentation at the WCLC 2023 conference focuses on early-stage non-small cell lung cancer (NSCLC), specifically lung adenocarcinoma. The aim of the study is to assess the effectiveness of consolidation-to-tumor ratio (CTR) and radiomics models for predicting invasiveness in patients with early lung adenocarcinoma. The researchers performed a retrospective analysis of patients from two hospitals and developed radiomics models using 2D and 3D imaging. The performance of CTR and the radiomics models were tested using receiver operating characteristic curves (ROC).<br /><br />A total of 818 patients from one hospital and 474 patients from another hospital were enrolled in the study. CTR and a radiomic score were identified as independent factors for predicting pathological invasiveness. The performance of CTR for 2D and 3D imaging was comparable, with similar area under curves (AUC). Patients in the primary cohort showed significant reference-free survival and overall survival. The radiomics models for both 2D and 3D imaging showed good performance and discrimination in the primary and independent cohorts. However, the 2D-related measurement was found to be more suitable for clinical use.<br /><br />In conclusion, this study found that both CTR and radiomics models, particularly using 2D imaging, were effective in predicting invasiveness in early-stage lung adenocarcinoma. The findings suggest that the 2D measurement may be more suitable for clinical applications. This research contributes to the field of screening and early detection of lung cancer, providing insights into innovative technology and techniques for assessing early-stage NSCLC.

Asset Subtitle

Meng-Min Wang

Meta Tag

Speaker Meng-Min Wang

Topic Early-Stage NSCLC: Innovation & New Technology

Keywords

WCLC 2023 conference

early-stage non-small cell lung cancer

NSCLC

lung adenocarcinoma

consolidation-to-tumor ratio

CTR

radiomics models

invasiveness prediction

2D imaging

3D imaging