2023 World Conference on Lung Cancer (Posters)-P2.22. Long-term Survival in Patients with Primitive Neuroectodermal Tumors of Thorax: Does Size Matter?

P2.22. Long-term Survival in Patients with Primitive Neuroectodermal Tumors of Thorax: Does Size Matter? - PDF(Abstract)

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This study aimed to evaluate the effect of tumor size and neoadjuvant therapy on long-term survival in patients with primitive neuroectodermal tumors (PNET) of the thorax. A total of 38 patients with PNET in the thorax were included in the study. Patient characteristics, including age, sex, and tumor size, were recorded, and the surgical procedures performed and neoadjuvant or adjuvant treatments received by the patients were documented. The survival status and time were followed up for all patients. <br /><br />The results showed that patients with tumors equal to or larger than 8 cm had worse survival compared to patients with smaller tumors. Tumor size was found to be a prognostic factor, with smaller tumor size associated with better overall survival. Patients with tumors smaller than 8 cm also had better disease-free survival. <br /><br />Additionally, neoadjuvant therapy was associated with better overall survival. Patients who received neoadjuvant chemo/radiotherapy had improved survival compared to those who did not. <br /><br />The study highlights the importance of tumor size and neoadjuvant treatment as prognostic factors in patients with PNET of the thorax. The findings suggest that smaller tumor size and receiving neoadjuvant therapy can improve survival in these patients. Further research is needed to confirm these findings and identify other potential prognostic markers for this rare yet aggressive tumor.

Asset Subtitle

Akif Turna

Meta Tag

Speaker Akif Turna

Topic Other Thoracic Malignancy

Keywords

tumor size

neoadjuvant therapy

long-term survival

primitive neuroectodermal tumors

PNET

thorax

patient characteristics

surgical procedures

adjuvant treatments

prognostic factors